During a joint press conference with Prime Minister Stefan Löfven, Biden said both countries talked about the important energy security and he underscored that the US felt the pipeline would "lock in greater reliance" on Russia and destabilize Ukraine.
"No country should be able to use energy as a weapon" says Biden, speaking of German-Russian gas line North Stream 2. "Russian gas can and should be a part of the European energy market, but that market must be open."
The pair also discussed issues including the refugee crisis, security and transatlantic cooperation during Biden's one-day visit to the Swedish capital.
Many central streets in Stockholm are closed during the visit, causing disruption to car and bus traffic. Public transport operator SL advises people to travel by rail as much as possible.
On 20th September it will be the turn of Löfven to travel to New York, to take part in a summit meeting on the refugee crisis, hosted by President Barack Obama, and including Ethiopia, Jordan, Mexico and Germany.
The police's website has a full list of road closures, which includes the areas round the Grand Hotel, including nearby water, and the government offices at Rosenbad.
For a full list of bus lines affected by the visit, see public transport operator SL's website.
Airspace over Stockholm is also closed for the visit.